Dr. Sarah R. Hengel
Hi! My name is Sarah and I’m an Assistant Professor at Tufts University in the Biology Department. My work is supported internally in the Tufts Biology Department by a Merrin Fund for Faculty Excellence and a R00 from the NIEHS.
My long-term goal is to mechanistically understand the intersection of repair proteins involved in DNA lesion recognition and homologous recombination. My research program is specifically focused on uncovering the underlying mechanisms of how DNA damage at replication forks is recognized by the human Shu complex and repaired by either RAD51-dependent or RAD52-dependent damage repair mechanisms.
My lab combines cell biology, biochemistry, biophysics, and single-molecule tweezers (C-trap) approaches to uncover novel insights into the mechanisms of DNA repair in aging, disease, and cancer.
When I’m not in the lab I’m spending time with my partner & our three doggos, painting, and advocating to make science a more inclusive and safe place for all humans.
PhD Graduate Students:
Steven Yu
Maggie Witham
Jamaurie James
Undergraduate Researchers:
Shoshana Daly
Nicole Dacey
Hannah Selverian
Laboratory Alumni:
Oluchi C. Ezekwenna M.S. Biology at Tufts University
Madeline J. Mueller B.S. Biochemistry at Tufts University